矢崎 亮 助教

九州大学大学院薬学研究院
環境調和創薬化学分野
Green Pharmaceutical Chemistry
Graduate School of Pharmaceutical Sciences, Kyushu University

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矢崎 亮 (Ryo Yazaki, Ph.D.)

略歴
平成14年3月 鹿児島県立加世田高等学校 卒業
平成14年4月 九州大学薬学部総合薬学科 入学
平成18年3月 同上 卒業
平成18年4月 東京大学大学院薬学研究科分子薬学専攻 入学
平成23年3月 同上 修了(薬学博士)
平成23年5月 Swiss Federal Institute of Technology Zurich 博士研究員
平成24年4月 九州大学大学院薬学研究院 助教 現在に至る

発表論文
1. Catalytic Aerobic Chemoselective α-Oxidation of Acylpyrazoles en Route to α-Hydroxy Acid Derivatives
Seiya Taninokuchi, Ryo Yazaki and Takashi Ohshima
Org. Lett. 2017, Article ASAP DOI: 10.1021/acs.orglett.7b01293

2. Catalytic Chemoselective Conjugate Addition of Amino Alcohols to α,β-Unsaturated Ester: Hydroxy Group over Amino Group and Conjugate Addition over Transesterification
Zhao Li, Masamichi Tamura, Ryo Yazaki, Takashi Ohshima
Chem. Pharm. Bull. 2017, 65, 19–21. DOI: 10.1248/cpb.c16-00333

3. Chemoselective Transesterification of Acrylate Derivatives for Functionalized Monomer Synthesis Using a Hard Zinc Alkoxide Generation Strategy
Daiki Nakatake, Ryo Yazaki, Takashi Ohshima
Eur. J. Org. Chem. 2016, 3696–3699. DOI: 10.1002/ejoc.201600737

4. Chemo- and Regioselective Direct Functional Group Installation through Catalytic Hydroxy Group Selective Conjugate Addition of Amino Alcohols to α,β-Unsaturated Sulfonyl Compounds
Zhao Li, Ryo Yazaki, Takashi Ohshima
Org. Lett., 2016, 18, 3350–3353. DOI: 10.1021/acs.orglett.6b01464

5. μ-Oxo-Dinuclear Iron(III) Catalyzed O-Selective Acylation of Aliphatic and Aromatic Amino Alcohols and Transesterification of tert-Alcohols
Rikiya Horikawa, Chika Fujimoto, Ryo Yazaki, Takashi Ohshima
Chem. Eur. J. 2016, 22, 12278–12281. DOI: 10.1002/chem.201602801(Press Release)

6. Transesterification Reaction Catalyzed by Recyclable Heterogeneous Zinc/Imidazole Catalyst
Daiki Nakatake, Ryo Yazaki, Yoshimasa Matsushima, Takashi Ohshima
Adv. Synth. Catal. 2016, 358, 2569–2574. DOI: 10.1002/adsc.201600229 (Press Release)
Synfacts 2016, 12, 1206. DOI: 10.1055/s-0036-1589328

7. Direct Catalytic Chemoselective α-Amination of Acylpyrazoles: A Concise Route to Unnatural α-Amino Acid Derivatives
Keisuke Tokumasu, Ryo Yazaki, Takashi Ohshima
J. Am. Chem. Soc., 2016, 138, 2664–2669. DOI: 10.1021/jacs.5b11773(Press Release)

8. A highly stable but highly reactive zinc catalyst for transesterification supported by a bis(imidazole) ligand
Daiki Nakatake, Yuki Yokote, Yoshimasa Matsushima, Ryo Yazaki, Takashi Ohshima
Green Chem., 2016, 18, 15241530. DOI: 10.1039/C5GC02056E

9. Chemoselective Catalytic Conjugate Addition of Alcohols over Amines
Shuhei Uesugi, Zhao Li, Ryo Yazaki, Takashi Ohshima
Angew. Chem. Int. Ed. 2014, 53, 1611-1615. DOI: 10.1002/anie.201309755

10. Cooperative Activation of Alkynes and Thioamides Functionalities; Direct Catalytic Asymmetric Conjugate Addition of Terminal Alkynes to α,β-Unsaturated Thioamides
Ryo Yazaki, Naoya Kumagai, Masakatsu Shibasaki
Chem. Asian, J. 2011, 6, 1778-1790. DOI: 10.1002/asia.201100050

11. Enantioselective Synthesis of a GPR40 Agonist AMG 837 via Catalytic Asymmetric Conjugate Addition of Terminal Alkyne to α,β-Unsaturated Thioamide
Ryo Yazaki, Naoya Kumagai, Masakatsu Shibasaki
Org. Lett. 2011, 13. 952-955. DOI: 10.1021/ol102998w

12. Direct Catalytic Asymmetric Conjugate Addition of Terminal Alkynes to α,β-Unsaturated Thioamides
Ryo Yazaki, Naoya Kumagai, Masakatsu Shibasaki
J. Am. Chem. Soc. 2010, 132, 10275-10277. DOI: 10.1021/ja105141x

13. Direct Catalytic Asymmetric Addition of Allyl Cyanide to Ketones via Soft Lewis Acid/Hard Brønsted Base/Hard Lewis base Catalysis
Ryo Yazaki, Naoya Kumagai, Masakatsu Shibasaki
J. Am. Chem. Soc. 2010, 132, 5523-5532. DOI: 10.1021/ja101687p

14. Direct Catalytic Asymmetric Addition of Allyl Cyanide to Ketones.
Ryo Yazaki, Naoya Kumagai, Masakatsu Shibasaki
J. Am. Chem. Soc. 2009, 131, 3195-3197. DOI: 10.1021/ja900001u

15. Direct Catalytic Asymmetric Addition of Allylic Cyanides to Ketoimines.
Ryo Yazaki, Tatsuya Nitabaru, Naoya Kumagai, Masakatsu Shibasaki
J. Am. Chem. Soc. 2008, 130, 14477-14479. DOI: 10.1021/ja806572b




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