Green Pharmaceutical Chemistry
Graduate School of Pharmaceutical Sciences, Kyushu University

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2018

Kenji Watanabe, Takashi Ohshima
Bioconjugation with Thiols by Benzylic Substitution
Chem. Eur. J. 2018, 24, 3959–3964. DOI: 10.1002/chem.201706149 (Press Release)

Yohei Matsumoto, Daiki Nakatake, Ryo Yazaki, Takashi Ohshima
An Expeditious Route to trans‐Configured Tetrahydrothiophenes Enabled by Fe(OTf)3‐Catalyzed [3+2] Cycloaddition of Donor–Acceptor Cyclopropanes with Thionoesters
Chem. Eur. J. 2018, 24. 6062–6066. DOI: 10.1002/chem.201800957

Takafumi Tanaka, Tsukushi Tanaka, Taro Tsuji, Ryo Yazaki, Takashi Ohshima
Strategy for Catalytic Chemoselective Cross-Enolate Coupling Reaction via a Transient Homocoupling Dimer
Org. Lett. 2018, 20, 3541–3544. DOI: 10.1021/acs.orglett.8b01313

Tsukushi Tanaka, Kayoko Hashiguchi, Takafumi Tanaka, Ryo Yazaki, Takashi Ohshima
Chemoselective Catalytic Dehydrogenative Cross-Coupling of 2-Acylimidazoles: Mechanistic Investigations and Synthetic Scope
ACS Catal. 2018, 8, 8430–8440. DOI:10.1021/acscatal.8b02361

Ryohei Yonesaki, Yuta Kondo, Walaa Akkad, Masanao Sawa, Kazuhiro Morisaki, Hiroyuki Morimoto, Takashi Ohshima
3‐Mono‐Substituted BINOL Phosphoric Acids as Effective Organocatalysts in Direct Enantioselective Friedel‐Crafts‐Type Alkylation of N‐Unprotected α‐Ketiminoester
Chem. Eur. J. Accepted Articles. DOI:10.1002/chem.201804078

Masanao Sawa, Shotaro Miyazaki, Ryohei Yonesaki, Hiroyuki Morimoto, Takashi Ohshima
Catalytic Enantioselective Decarboxylative Mannich-Type Reaction of N-Unprotected Isatin-Derived Ketimines
Org. Lett. Article ASAP. DOI:10.1021/acs.orglett.8b02306